Anti-CECR2/FITC抗体

产品编号YB-13824R-FITC

英文名称Anti-CECR2/FITC

中文名称FITC标记的猫眼综合征染色体候选基因2抗体

别    名Cat eye syndrome chromosome region candidate 2; CECR2_HUMAN; KIAA1740.

Anti-CECR2/FITC抗体

说 明 书100ul  

研究领域细胞生物  免疫学  细菌及病毒  结合蛋白  细胞表面分子  淋巴细胞  t-淋巴细胞  表观遗传学  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Chicken, Dog, Horse,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量164kDa

Anti-CECR2/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human CECR2

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-CECR2/FITC抗体

产品介绍background:

Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. This family consists of several mammalian T-cell surface antigen CD2 proteins as well as homologous African swine fever virus sequences.

Function:

Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis.

Subunit:

Part of the CECR2-containing remodeling factor (CERF) complex which contains CECR2 and SMARCA1. Interacts with acetylated lysine residues on histone H2A and H3 (in vitro). Interacts with LRPPRC.

Tissue Specificity:

Highly expressed in skeletal muscle, Anti-CECR2/FITC抗体thymus, placenta and lung. Expressed at lower level in brain, heart, colon, spleen, kidney.

Similarity:

Contains 1 bromo domain.

Database links:

Entrez Gene: 27443 Human

Omim: 607576 Human

SwissProt: Q9BXF3 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.