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Anti-C1GALT1/FITC抗体
产品编号YB-9685R-FITC
英文名称Anti-C1GALT1/FITC
中文名称FITC标记的N-乙酰半乳糖胺糖蛋白3、β-半乳糖转移酶1抗体
别 名B3Gal T8; Beta 1 3 galactosyltransferase; C1GALT; Core 1 beta1 3 galactosyltransferase 1; Core 1 beta3 Gal T; Core 1 O glycan T synthase; Core 1 synthase glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1 3 galactosyltransferase; Glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; T synthase.
Anti-C1GALT1/FITC抗体
说 明 书100ul
研究领域心血管 细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40kDa
细胞定位细胞膜
Anti-C1GALT1/FITC抗体性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human C1GALT1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-C1GALT1/FITC抗体
产品介绍background:
C1GALT1 is a glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is synthesized by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended O-glycans in glycoproteins. C1GALT1 plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Subunit:
Homodimer; disulfide-linked (By similarity).Anti-C1GALT1/FITC抗体 Interacts with the C1GALT1C1 chaperone; required for galactosyltransferase activity.
Subcellular Location:
Membrane.
Tissue Specificity:
Widely expressed. Highly expressed in kidney, heart, placenta and liver.
Similarity:
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
Database links:
Entrez Gene: 56913 Human
Omim: 610555 Human
SwissProt: Q9NS00 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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