Anti-phospho-c-Myb (Ser532)/FITC抗体

产品编号YB12917R-FITC

英文名称Anti-phospho-c-Myb (Ser532)/FITC

中文名称FITC标记的磷酸化原癌基因cMAF抗体

别    名c-Myb (phospho S532); p-c-Myb (phospho S532); Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.

Anti-phospho-c-Myb (Ser532)/FITC抗体

说 明 书100ul  

产品类型磷酸化抗体

研究领域肿瘤  细胞生物  染色质和核信号  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量84kDa

Anti-phospho-c-Myb (Ser532)/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthesised phosphopeptide derived from human c-Myb around the phosphorylation site of Ser532

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-phospho-c-Myb (Ser532)/FITC抗体

产品介绍background:

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Function:

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Subcellular Location:

Nucleus.

Post-translational modifications:

Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.

Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.

Similarity:

Contains 3 HTH myb-type DNA-binding domains.

Anti-phospho-c-Myb (Ser532)/FITC抗体Database links:

Entrez Gene: 317776 Cow

Entrez Gene: 4602 Human

Entrez Gene: 17863 Mouse

Entrez Gene: 498982 Rat

Omim: 189990 Human

SwissProt: P46200 Cow

SwissProt: P10242 Human

SwissProt: P06876 Mouse

Unigene: 606320 Human

Unigene: 52109 Mouse

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.