Anti-Cyclin M3/FITC抗体

产品编号YB-12045R-FITC

英文名称Anti-Cyclin M3/FITC

中文名称FITC标记的周期素M3抗体

别    名ACDP3; Ancient conserved domain containing protein 3; CNNM3; DKFZp434I1016; FLJ20018; Metal transporter CNNM3; CNNM3_HUMAN.

Anti-Cyclin M3/FITC抗体

说 明 书100ul  

研究领域细胞生物  免疫学  信号转导  细胞周期蛋白  通道蛋白  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量76kDa

细胞定位细胞膜

Anti-Cyclin M3/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Cyclin M3

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-Cyclin M3/FITC抗体

产品介绍background:

Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.

Function:

Cyclin M3 is a probable metal transporter. There are three named isoforms.

Subcellular Location:

Integral to plasma membrane; Multi-pass membrane protein

Tissue Specificity:

Widely expressed. Expressed at higher level in heart and spleen.

Anti-Cyclin M3/FITC抗体DISEASE:

Similarity:

Belongs to the ACDP family.

Contains 2 CBS domains.

Contains 1 DUF21 domain.

Database links:

UniProtKB/Swiss-Prot: Q8NE01.1

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.