Anti-C1orf86/FITC抗体

产品编号YB15079R-FITC

英文名称Anti-C1orf86/FITC

中文名称FITC标记的1号染色体开放阅读框86抗体

别    名C1orf86; CA086_HUMAN; Chromosome 1 open reading frame 86; FP7162; RP11-181G12.3; Uncharacterized protein C1orf86.

Anti-C1orf86/FITC抗体

说 明 书100ul  

研究领域免疫学  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量20kDa

Anti-C1orf86/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human C1orf86

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-C1orf86/FITC抗体

产品介绍background:

Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.

Subunit:

Component of the Fanconi anemia (FA) complex. Interacts with FANCA; interaction is direct. Interacts with REV1. Reported to bind monoubiquitinated REV1; however it binds better to non-ubiquitinated REV1 (PubMed:22266823).

Subcellular Location:

Nucleus. Chromosome. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8.

Similarity:

Contains 1 UBZ-type zinc finger.

Anti-C1orf86/FITC抗体Database links:

Entrez Gene: 199990 Human

Omim: 615183 Human

SwissProt: Q6NZ36 Human

Unigene: 107101 Human

Important Note:

This product as s