Anti-C8orf4/FITC抗体

产品编号YB-15289R-FITC

英文名称Anti-C8orf4/FITC

中文名称FITC标记的8号染色体开放阅读框4抗体

别    名C8orf4; CH004_HUMAN; Chromosome 8 open reading frame 4; Human thyroid cancer 1; MGC22806; TC-1; TC1; Thyroid cancer protein 1; Uncharacterized protein C8orf4.

Anti-C8orf4/FITC抗体

说 明 书100ul  

研究领域细胞生物  免疫学  染色质和核信号  信号转导  表观遗传学  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量12kDa

Anti-C8orf4/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human C8orf4

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-C8orf4/FITC抗体

产品介绍background:

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]

Function:

May decrease apoptosis.

Subunit:

Monomer.

Tissue Specificity:

Ubiquitous. Expressed in thyroid papillary carcinoma.

Anti-C8orf4/FITC抗体Database links:

Entrez Gene: 56892 Human

Omim: 607702 Human

SwissProt: Q9NR00 Human

Unigene: 591849 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.