血栓素B2(一种新发现的抑癌基因)抗体

规格：1mg/1ml

英文名： TBX2

别名： T-box2; Tbx21; T-box Protein 2; T-box transcription factor TBX2; T-box protein 2; FLJ10169; HGNC: 11597; T box 2; T box transcription factor TBX2; TBX2_HUMAN; TBX2.

分子量： 74kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human TBX2

交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,

血栓素B2(一种新发现的抑癌基因)抗体细胞定位：

产品介绍：background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. Function: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb血栓素B2(一种新发现的抑癌基因)抗体 pattern formation. Acts as a negative regulator of PML function in cellular senescence. Subunit: Interacts with PML (isoform-PML-2, isoform PML-3 and isoform PML-4). Subcellular Location: Nucleus (Potential). Tissue Specificity: Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary. Similarity: Contains 1 T-box DNA-binding domain. Gene ID: 30009 D血栓素B2(一种新发现的抑癌基因)抗体atabase links: Entrez Gene: 30009 Human Entrez Gene: 57765 Mouse Entrez Gene: 303496 Rat Omim: 604895 Human SwissProt: Q9UL17 Human SwissProt: Q9JKD8 Mouse Unigene: 272409 Human Unigene: 94519 Mouse Unigene: 144930 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

血栓素B2(一种新发现的抑癌基因)抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  免疫学  染色质和核信号  转录调节因子  表观遗传学  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid