磷酸蛋白聚糖PTPRZ抗体

规格：1mg/1ml

英文名： PTP zeta

别名： Phosphacan; 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; Phosphacan; Protein tyrosine phosphatase receptor type Z polypeptide 2; Protein tyrosine phosphatas

分子量： 251kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human Phosphac

交叉反应：Human, Mouse, Rat,

细胞定位：细胞膜

磷酸蛋白聚糖PTPRZ抗体产品介绍：background: PTP zeta (receptor-type protein tyrosine phosphatase zeta) is a type I membrane protein chondroitin sulfate proteoglycan with a transmembrane domain and intracellular tyrosine phosphatase domains. PTP zeta may be involved in the regulation of specific developmental processes in the CNS. PTP zeta is developmentally regulated in the brain and specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. PTP zeta belongs to the protein-tyrosine phosphatase family and contains 1 eukaryotic-type carbonic磷酸蛋白聚糖PTPRZ抗体 anhydrase domain, 1 fibronectin type III domain and 2 tyrosine-protein phosphatase domains. Function: May be involved in the regulation of specific developmental processes in the CNS. Subunit: The carbonic-anhydrase like domain binds to contactin (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain. Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. Contains 磷酸蛋白聚糖PTPRZ抗体1 alpha-carbonic anhydrase domain. Contains 1 fibronectin type-III domain. Contains 2 tyrosine-protein phosphatase domains. Database links: Entrez Gene: 5803 Human Entrez Gene: 19283 Mouse Entrez Gene: 25613 Rat Omim: 176891 Human SwissProt: P23471 Human SwissProt: Q62656 Rat Unigene: 489824 Human Unigene: 10088 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

磷酸蛋白聚糖PTPRZ抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  神经生物学  信号转导  激酶和磷酸酶  细胞类型标志物  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid