嘌呤霉素敏感性氨肽酶蛋白抗体

规格：1mg/1ml

英文名： NPEPPS

别名： PSAP; AAP-S; aminopeptidase puromycin sensitive; Cytosol alanyl aminopeptidase; METALLOPROTEASE 100; METALLOPROTEASE MP100; MP 100; MP100; Npepps; PSA; PSA_HUMAN; Puromycin sensitive aminopeptidase; P

分子量： 103kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human NPEPPS

交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

细胞定位：细胞浆

嘌呤霉素敏感性氨肽酶蛋白抗体产品介绍：background: Puromycin-sensitive aminopeptidase is a 100kDa zinc metallopeptidase which degrades neuropeptides by removing amino acid residues from the amino-terminus. The protein is the most abundant aminopeptidase in the brain, however it is not exclusive to that organ. It is localized primarily in the cytoplasm, and plays a role in the metabolism of neuropeptides in nerve terminals and synaptic clefts. The human PSA gene maps to chromosome 17q 2-32. Function: Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays 嘌呤霉素敏感性氨肽酶蛋白抗体a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in liver, epithelium of renal tubules, epithelium of small and 嘌呤霉素敏感性氨肽酶蛋白抗体large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). Similarity: Belongs to the peptidase M1 family. Gene ID: 9520 Database links: Entrez Gene: 9520 Human Entrez Gene: 19155 Mouse Entrez Gene: 50558 Rat Omim: 606793 Human SwissProt: P55786 Human SwissProt: Q11011 Mouse Unigene: 443837 Human Unigene: 29824 Mouse   Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

嘌呤霉素敏感性氨肽酶蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  神经生物学  Alzheimer's  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid