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神经元电压门控钙通道γ3/L-type Ca++CP γ3抗体
规格:1mg/1ml
英文名: CACNG3
别名: CACNG 3; Cacng2; Calcium channel voltage dependent gamma subunit 3; Neuronal voltage gated calcium channel gamma 3 subunit; Voltage dependent calcium channel gamma 3 subunit; Voltage gated calcium cha
分子量: 36kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
免疫原:KLH conjugated synthetic peptide derived from human CACNG3
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞膜
神经元电压门控钙通道γ3/L-type Ca++CP γ3抗体产品介绍:background: CACNG3 belongs to the PMP-22/EMP/MP20 family, CACNG subfamily. It is thought to stabilize the calcium channel in an inactivated (closed) state. CACNG3 is a candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis. Function: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates o神经元电压门控钙通道γ3/L-type Ca++CP γ3抗体f activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). Subunit: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as an auxiliary subunit for AMPA-selective glutamate receptor神经元电压门控钙通道γ3/L-type Ca++CP γ3抗体s (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG4, CACNG5, CACNG7 and CACNG8 (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. Database links: UniProtKB/Swiss-Prot: O60359.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经元电压门控钙通道γ3/L-type Ca++CP γ3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 通道蛋白 细胞膜受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid
- 询价产品:神经元电压门控钙通道γ3/L-type Ca++CP γ3抗体 CACNG3
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