岩藻糖基转移酶7抗体

规格：1mg/1ml

英文名： FUT7

别名： 3)-fucosyltransferase; Alpha (1,3) fucosyltransferase; Alpha-(1; Fuc-TVII; Fucosyltransferase 7; Fucosyltransferase VII; FucT VII; FucT-VII; FUT7; FUT7_HUMAN; Galactoside 3 L fucosyltransferase; Galac

分子量： 39kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human FUT7/Fuc

交叉反应：Human, Mouse, Rat, Horse,

细胞定位：细胞浆 细胞膜

岩藻糖基转移酶7抗体产品介绍：background: Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles岩藻糖基转移酶7抗体, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Alpha 1,3-fucosyltransferase VII (FucT-VII) mediates the targeting of effector T cells to sites of inflammation by modifying surface ligands which are compatible to岩藻糖基转移酶7抗体 endothelial selectins (7). Function: May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens. Subcellular Location: Golgi apparatus; Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi. Tissue Specificity: Leukocytic/myeloid lineage cells. Similarity: Belongs to the glycosyltransferase 10 family. Database links: Database links : UniProtKB/Swiss-Prot: Q11130.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

岩藻糖基转移酶7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  发育生物学  信号转导  新陈代谢  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid