基质金属蛋白酶-10抗体

规格：1mg/1ml

英文名： MMP10

别名： Matrix metalloproteinase 10; Matrix metalloproteinase-10; matrix metalloproteinase 10; MMP-10; Mmp10; MMP10_HUMAN; SL 2; SL2; STMY 2; Stromelysin 2; Stromelysin II; Stromelysin-2; Stromelysin2; Strome

分子量： 43kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human MMP10

交叉反应：Human, Mouse, Rat,

细胞定位：细胞外基质 分泌型蛋白

基质金属蛋白酶-10抗体产品介绍：background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by 基质金属蛋白酶-10抗体extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Function: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Subcellular Location: Secreted, extracellular space, extracellular matrix (Probable). Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. Gene ID: 4319 Database links: Entrez Gene: 4319 Human Entrez Gene: 17384 Mouse基质金属蛋白酶-10抗体 Entrez Gene: 117061 Rat Omim: 185260 Human SwissProt: P09238 Human SwissProt: O55123 Mouse SwissProt: P07152 Rat Unigene: 2258 Human Unigene: 14126 Mouse Unigene: 9946 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 合成与降解（Synthesis and Degradation） MMP10主要用于一些恶性肿瘤，如乳腺癌、胃肠道癌、卵巢癌等与转移浸润的研究。

基质金属蛋白酶-10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  心血管  细胞生物  细胞外基质  泛素  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid