氧化还原酶GlyR1/核蛋白60抗体

规格：1mg/1ml

英文名： GLYR1

别名： 3 hydroxyisobutyrate dehydrogenase like protein; 3-hydroxyisobutyrate dehydrogenase-like protein; BM045; Cytokine like nuclear factor n pac; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1

分子量： 61kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human GLYR1/NP

交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Monkey,

细胞定位：细胞核

氧化还原酶GlyR1/核蛋白60抗体产品介绍：background: NP60 is a 553 amino acid nuclear protein that regulates the phosphorylation and activation of p38 alpha in response to stress. There are five isoforms of NP60 that are produced as a result of alternative splicing events. Function: May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14氧化还原酶GlyR1/核蛋白60抗体 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Subunit: Interacts with MAPK14. Subcellular Location: Nucleus. Similarity: Belongs to the氧化还原酶GlyR1/核蛋白60抗体 3-hydroxyisobutyrate dehydrogenase family. NP60 subfamily. Contains 1 A.T hook DNA-binding domain. Contains 1 PWWP domain. Database links: Entrez Gene: 84656 Human Entrez Gene: 74022 Mouse Entrez Gene: 360477 Rat Omim: 610660 Human SwissProt: Q49A26 Human SwissProt: Q922P9 Mouse SwissProt: Q5RKH0 Rat Unigene: 387255 Human Unigene: 21652 Mouse Unigene: 2639 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

氧化还原酶GlyR1/核蛋白60抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  信号转导  激酶和磷酸酶  表观遗传学  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid