尤文氏瘤相关抗原1抗体

规格：1mg/1ml

英文名： ETAA1/ETAA16

别名： Etaa1; ETAA1_HUMAN; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16; ETAA16.

分子量： 103kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human ETAA1/ET

交叉反应：Human,

细胞定位：细胞浆

尤文氏瘤相关抗原1抗体产品介绍：background: ETAA16 (Ewing's tumor-associated antigen 16), also known as ETAA1, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA16 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen尤文氏瘤相关抗原1抗体 in Ewing's family of tumour cell lines. The gene encoding ETAA16 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases 尤文氏瘤相关抗原1抗体are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Gene ID: 54465 Database links: Entrez Gene: 54465 Human Omim: 613196 Human SwissProt: Q9NY74 Human Unigene: 353022 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

尤文氏瘤相关抗原1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  免疫学  

储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid