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半乳糖神经酰胺磺基转移酶抗体
规格:1mg/1ml
英文名: GAL3ST1
别名: 3' phosphoadenosine 5' phosphosulfate:GalCer sulfotransferase; 3' phosphoadenylylsulfate:galactosylceramide 3' sulfotransferase; 3''-phosphoadenosine-5''-phosphosulfate:GalCer sulfotransferase; 3''-ph
分子量: 49kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
免疫原:KLH conjugated synthetic peptide derived from human GAL3ST1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:
半乳糖神经酰胺磺基转移酶抗体产品介绍:background: Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008] Function: Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the 半乳糖神经酰胺磺基转移酶抗体synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes (By similarity). Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro). Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in kidney proximal tubule半乳糖神经酰胺磺基转移酶抗体, gastric mucosa and adenocarcinoma. Highly expressed in renal cell carcinoma cell lines. Similarity: Belongs to the galactose-3-O-sulfotransferase family. Gene ID: 9514 Database links: Entrez Gene: 9514 Human Omim: 602300 Human SwissProt: Q99999 Human Unigene: 17958 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
半乳糖神经酰胺磺基转移酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid
- 询价产品:半乳糖神经酰胺磺基转移酶抗体 GAL3ST1
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