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内皮细胞清道夫受体抗体
规格:1mg/1ml
英文名: SCARF1
别名: Acetyl LDL receptor; Endothelial cells scavenger receptor; SCARF1; Scavenger receptor class F member 1; Scavenger receptor expressed by endothelial cells 1; Scavenger receptor expressed by endothelial
分子量: 85kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
免疫原:KLH conjugated synthetic peptide derived from human SCARF1
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位:细胞膜
内皮细胞清道夫受体抗体产品介绍:background: The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] Function: Mediates the binding and degradation of acetylated low 内皮细胞清道夫受体抗体density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. Subunit: Heterophilic interaction with SREC2 via its extracellular domain. The heterophilic interaction is suppressed by the presence of ligand such as Ac-LDL. Interacts with AVIL (By similarity). Subcellular Location: Membrane. Tissue Specificity: Endothelial cells. Similarity内皮细胞清道夫受体抗体: Contains 6 EGF-like domains. Gene ID: 8578 Database links: Entrez Gene: 8578 Human Omim: 607873 Human SwissProt: Q14162 Human Unigene: 647430 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
内皮细胞清道夫受体抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid
- 询价产品:内皮细胞清道夫受体抗体 SCARF1
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