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白介素11抗体
规格:1mg/1ml
英文名: IL-11
别名: Interleukin-11; Adipogenesis inhibitory factor; AGIF; IL 11; IL11; Interleukin 11; Oprelvekin; IL11_HUMAN.
分子量: 19kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
免疫原:KLH conjugated synthetic peptide derived from human IL-11
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig,
细胞定位:分泌型蛋白
白介素11抗体产品介绍:background: Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to白介素11抗体 prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy. Function: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Subcellular Location: Secreted. Similarity: Belongs to the IL-6 superfamily. Gene ID: 3589 Database links:白介素11抗体 Entrez Gene: 3589 Human Omim: 147681 Human SwissProt: P20809 Human Unigene: 467304 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白介素11,是一种多向性细胞因子。很多细胞都能合成IL11,如:内皮细胞、纤维母细胞、软骨细胞、滑膜细胞、成骨细胞、上皮细胞、神经元、胸腺等。正常的血清中,IL11表达很少或处在检测水平之下。对造血系统的功能包括:干细胞、巨核细胞、骨髓细胞、红细胞和B淋巴细胞的增生和发育。对造血系统之外也具有多相性的作用,有些是刺激和促进增生,有些是抑制作用。人、大鼠、小鼠的IL-11的前体有199个氨基酸。成熟形态为178个氨基酸。
白介素11抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 免疫学 神经生物学 干细胞 血管内皮细胞 淋巴细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid
- 询价产品:白介素11抗体 IL-11
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