赖氨酰氧化酶样1抗体

规格：1mg/1ml

英文名： LOXL1

别名： Lysyl oxidase like 1; LOL; LOXL1_HUMAN； LOXL; Lysyl oxidase homolog 1; Lysyl oxidase like 1; Lysyl oxidase like protein 1.

分子量： 53kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human LOXL1

交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

细胞定位：分泌型蛋白

赖氨酰氧化酶样1抗体产品介绍：background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member 赖氨酰氧化酶样1抗体of the family. [provided by RefSeq, Jul 2008] Function: Involved in hearing. Required for normal function of hair cells in the inner ear. Subcellular Location: Secreted, extracellular space. DISEASE: Deafness, autosomal recessive, 77 (DFNB77) [MIM:613079]: A form of non-syndromic deafness characterized by preserved low-frequency hearing, and a trend toward mild to moderate mid-frequency and high-frequency hearing loss during childhood and adolescence. Hearing loss progresses to become moderate to severe at mid and high frequencies during a赖氨酰氧化酶样1抗体dulthood. Similarity: Contains 14 PLAT domains. Gene ID: 4016 Database links: Entrez Gene: 4016 Human Entrez Gene: 16949 Mouse Entrez Gene: 315714 Rat Omim: 153456 Human SwissProt: Q08397 Human SwissProt: P97873 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

赖氨酰氧化酶样1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  细胞生物  免疫学  信号转导  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid