磷酸化巨噬细胞集落刺激因子受体抗体

规格：1mg/1ml

英文名： phospho-MCSF Receptor (Tyr561)

别名： MCSF Receptor (phospho Y561); p-MCSF Receptor (phospho Y561); C FMS; CD 115; CD115; CD115 antigen; CFMS; Colony stimulating factor 1 receptor; Colony stimulating factor I receptor; CSF 1 R; CSF 1R; CS

分子量： 120kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human phospho-

交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

细胞定位：细胞膜

磷酸化巨噬细胞集落刺激因子受体抗体产品介绍：background: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy. Function: Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34. 磷酸化巨噬细胞集落刺激因子受体抗体Subcellular Location: Membrane. Tissue Specificity: Expressed in bone marrow and in differentiated blood mononuclear cells. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 protein kinase domain. Gene ID: 1436 Database links: Entrez Gene: 1436 Human Entrez Gene: 磷酸化巨噬细胞集落刺激因子受体抗体12978 Mouse Omim: 164770 Human SwissProt: P07333 Human SwissProt: P09581 Mouse Unigene: 586219 Human Unigene: 22574 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

磷酸化巨噬细胞集落刺激因子受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  免疫学  信号转导  激酶和磷酸酶  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid