组蛋白去乙酰化酶复合亚基SAP30抗体

规格：1mg/1ml

英文名： SAP30

别名： 30 kDa Sin3-associated polypeptide; Histone deacetylase complex subunit SAP 30; Histone deacetylase complex subunit SAP30; MSin3A associated polypeptide p30; SAP 30; Sap30; SAP30_HUMAN; Sin3 associate

分子量： 23kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human SAP30

交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Guinea Pig, Cat, Spider Monkey

细胞定位：细胞核

组蛋白去乙酰化酶复合亚基SAP30抗体产品介绍：background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Jul 2008] Function: Involved in the functional recruitment of the Sin3-histone deacetylase complex组蛋白去乙酰化酶复合亚基SAP30抗体 (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. Subcellular Location: Nucleus. Tissue Specificity: Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus; lowest levels in brain,组蛋白去乙酰化酶复合亚基SAP30抗体 placenta, lung and kidney. Similarity: Belongs to the SAP30 family. Database links: Entrez Gene: 8819 Human Entrez Gene: 60406 Mouse Omim: 603378 Human SwissProt: O75446 Human SwissProt: O88574 Mouse Unigene: 591715 Human Unigene: 118 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

组蛋白去乙酰化酶复合亚基SAP30抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  表观遗传学  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid