-
- 地区
- 全部
-
- 会员级别
- 全部
甲状旁腺激素相关受体蛋白2抗体
规格:1mg/1ml
英文名: PTH2R
别名: Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor; PTH 2 receptor; PTH2 receptor; Pth2r; PTH2R_HUMAN; Pthr 2; Pthr2.
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
免疫原:KLH conjugated synthetic peptide derived from human PTH2R
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
甲状旁腺激素相关受体蛋白2抗体产品介绍:Function: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. Subunit: Interacts (via N-terminal extracellular domain) with PTHLH and PTH. Homodimer in the absence of bound ligand. Peptide hormone binding leads to dissociation of the homodimer. Interacts (via C-terminus) with the heterodimer formed by GNG2 and GNB1. Subcellular Location: Cell membrane. 甲状旁腺激素相关受体蛋白2抗体Tissue Specificity: Expressed abundantly in brain and pancreas. Also expressed in the testis. DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:Rare autosomal dominant disorder characterized by a short-limbed dwarfism associated with hypercalcemia and normal or low serum concentrations of the two parathyroid hormones. Similarity: Belongs to the G-protein coupled receptor 2 family. Database links: Entrez Gene: 5746 Human Entrez Gene: 213527 Mouse Entrez Gene甲状旁腺激素相关受体蛋白2抗体: 81753 Rat Omim: 601469 Human SwissProt: P49190 Human SwissProt: Q91V95 Mouse SwissProt: P70555 Rat Unigene: 570296 Human Unigene: 294225 Mouse Unigene: 10601 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲状旁腺激素相关受体蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 生长因子和激素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid
- 询价产品:甲状旁腺激素相关受体蛋白2抗体 PTH2R
- 询价数量: /个
- 联系人:
- 联系电话: