白介素-5受体α链抗体IL-5Rα

规格：1mg/1ml

英文名： IL5RA

别名： Interleukin-5 receptor alpha; CD125 antigen; CDw125; HSIL5R3; IL5R; IL-5R; Interleukin 5 Receptor alpha; Interleukin 5 receptor subunit alpha; interleukin 5 receptor type 3; MGC26560; IL5RA; IL-5R alp

分子量： 46kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human IL-5R al

交叉反应：Human, Mouse, Rat, Cow, Rabbit,

细胞定位：细胞膜

白介素-5受体α链抗体IL-5Rα产品介绍：background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. Function: This is the receptor for interleukin-5. The alpha chain binds 白介素-5受体α链抗体IL-5Rαto IL5. Subunit: Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with SDCBP. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed on eosinophils and basophils. Similarity: Belongs to the type I cytokine receptor family. Type 5 subfamily. Gene ID: 3568 Database links: Entrez 白介素-5受体α链抗体IL-5RαGene: 3568 Human Entrez Gene: 16192 Mouse Omim: 147851 Human SwissProt: Q01344 Human SwissProt: P21183 Mouse Unigene: 207105 Human Unigene: 68876 Human Unigene: 3448 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白介素-5受体α链抗体IL-5Rα产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  免疫学  转录调节因子  细胞膜受体  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid