G蛋白β3抗体/鸟嘌呤核苷酸结合蛋白β亚基3抗体

规格：1mg/1ml

英文名： GNB3

别名： G protein beta 3; Gnb3; Guanine nucleotide binding protein (G protein), beta polypeptide 3; Guanine nucleotide binding protein G; Hypertension associated protein; IG; SG; Transducin beta chain 3; Tsub

分子量： 37kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human G protei

交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

细胞定位：

G蛋白β3抗体/鸟嘌呤核苷酸结合蛋白β亚基3抗体产品介绍：background: G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. G蛋白β3抗体/鸟嘌呤核苷酸结合蛋白β亚基3抗体Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Subunit: G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2. Similarity: Belongs to the WD repeat G protein beta family. Contains 7 WD repeats. Database links: Entrez Gene: 2784 Human Entrez Gene: 14695 Mouse Entrez GeneG蛋白β3抗体/鸟嘌呤核苷酸结合蛋白β亚基3抗体: 60449 Rat Omim: 139130 Human SwissProt: P16520 Human SwissProt: Q61011 Mouse SwissProt: P52287 Rat Unigene: 631657 Human Unigene: 68889 Mouse Unigene: 27065 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

G蛋白β3抗体/鸟嘌呤核苷酸结合蛋白β亚基3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  心血管  细胞生物  免疫学  转录调节因子  结合蛋白  G蛋白偶联受体  G蛋白信号  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid