NADH氧化还原酶辅酶1抗体

规格：1mg/1ml

英文名： NDUFA1

别名： CI MWFE; Complex I MWFE; MWFE; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1; NADH ubiquinone oxidoreductase (complex 1); NADH ubiqu

分子量： 8kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human NDUFA1 (

交叉反应：Human, Mouse, Rat, Dog, Horse,

细胞定位：细胞浆 细胞膜 线粒体

NADH氧化还原酶辅酶1抗体产品介绍：background: NDUFA1 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1) is an essential component of the multisubunit NADH ubiquinone oxidoreductase (complex 1), the first enzyme complex in the mitochondrial respiratory chain. Complex I transfers electrons from NADH to the respiratory chain via ubiquinone. Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Subunit: NADH氧化还原酶辅酶1抗体Complex I is composed of 45 different subunits. Subcellular Location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. Tissue Specificity: Primarily expressed in heart and skeletal muscle. DISEASE: Defects in NDUFA1 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specificNADH氧化还原酶辅酶1抗体 encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Similarity: Belongs to the complex I NDUFA1 subunit family. Database links: UniProtKB/Swiss-Prot: O15239.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NADH氧化还原酶辅酶1抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  细胞生物  免疫学  转录调节因子  线粒体  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid