蛋白酪氨酸激酶9抗体

规格：1mg/1ml

英文名： PTK9

别名： A6; A6 protein tyrosine kinase; Protein A6; Protein tyrosine kinase 9; PTK9; PTK9 protein tyrosine kinase 9; TWF 1; TWF1; Twinfilin 1; Twinfilin actin binding protein, homolog 1; Twinfilin; Twinfilin,

分子量： 40kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human PTK9

交叉反应：Human, Mouse, Rat, Pig, Cow,

细胞定位：

蛋白酪氨酸激酶9抗体产品介绍：background: PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. Subunit: Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF2 and phosphoinositides, PI(4,5)P2. When bound to PI(4,5)P2, it is down-regulated. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich蛋白酪氨酸激酶9抗体 cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts. Tissue Specificity: Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. Post-translational modifications: Phosphorylated on serine and threonine residues. Similarity: Belongs to the actin-binding proteins ADF family. 蛋白酪氨酸激酶9抗体Twinfilin subfamily. Contains 2 ADF-H domains. Database links: Entrez Gene: 5756 Human Entrez Gene: 506683 Cow Entrez Gene: 19230 Mouse Entrez Gene: 315265 Rat Omim: 610932 Human SwissProt: Q56JV6 Cow SwissProt: Q12792 Human SwissProt: Q91YR1 Mouse SwissProt: Q5RJR2 Rat Unigene: 5944 Cow Unigene: 189075 Human Unigene: 309867 Mouse Unigene: 162971 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

蛋白酪氨酸激酶9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：免疫学  信号转导  结合蛋白  细胞骨架  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid