脑胶质瘤发病机制相关蛋白1抗体

规格：1mg/1ml

英文名： GLIPR1

别名： ALKN2972; GLIPR1-like protein 1; MGC26856; PRO7434; UNQ2972/PRO7434; GLIPR1; GLIPR; RTVP1; GliPR 1; Protein RTVP-1; Glioma pathogenesis-related protein 1; GLIP1_HUMAN.

分子量： 27kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

免疫原：KLH conjugated synthetic peptide derived from human GLIPR1

交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,

细胞定位：细胞膜

脑胶质瘤发病机制相关蛋白1抗体产品介绍：background: This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] Subcellular Location: Single-pass membrane protein. Tissue Specificity: According to PubMed:8973356脑胶质瘤发病机制相关蛋白1抗体, it is ubiquitously expressed with high levels in lung and kidney and low levels in heart and liver. Highly expressed in cell lines derived from nervous system tumors arising from glia, low or absent in non-glial-derived nervous system tumor cell lines. Also found in fetal kidney. According to PubMed:7607567 it is expressed only in brain tumor glioblastoma multiforme/astrocytoma and not in other nervous system tumors or normal fetal or adult tissues. Similarity: Belongs to the CRISP family. Gene ID: 11010 Database links: Entrez Gene: 脑胶质瘤发病机制相关蛋白1抗体11010 Human Entrez Gene: 299783 Rat Omim: 602692 Human SwissProt: P48060 Human Unigene: 205558 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

脑胶质瘤发病机制相关蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：肿瘤  细胞生物  免疫学  发育生物学  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid