别名：亚叶酸钙; N-(4-(((2-氨基-5-甲酰-5,6,7,8-四氢-4-羟基-6-蝶啶)甲基)氨基)苯甲酰)-L-谷氨酸钙盐
Chemical Name:N-(4-(((2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid calcium salt
英文名：Leucovorin Calcium;Calcium folinate;Folinic acid calcium salt
分子式：C20H21N7O7.Ca
分子量： 511.51
外观： White or light yellow amorphous crystalline powder
纯度： >99%
CAS No：1492-18-8
Biological Activity:
Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.