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抗体来源 | Rabbit | |||
克隆类型 | polyclonal | |||
交叉反应 | hu, mo, rat | |||
产品类型 | 一抗 | |||
研究领域 | 细胞生物 神经生物学 G蛋白偶联受体 免疫荧光 | |||
蛋白分子量 | predicted molecular weight: 46kDa | |||
性 状 | Lyophilized or Liquid | |||
浓 度 | 1mg/1ml | |||
免 疫 原 | KLH conjugated synthetic peptide derived from hu MCHR/GPR24 | |||
亚 型 | IgG | |||
纯化方法 | affinity purified by Protein A | |||
储 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 | |||
产品应用 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
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保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. | |||
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
MCHR, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR does not seem to bind somatostatin. |