丝氨酸蛋白酶8抗体 Anti-PRSS8 货号bs-6064R

抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 hu, mo, rat
产品类型一抗
研究领域肿瘤细胞生物激酶和磷酸酶肿瘤细胞生物标志物免疫荧光流氏细胞检测
蛋白分子量 predicted molecular weight: 36kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免疫原 KLH conjugated synthetic peptide derived from human PRSS8
亚    型 IgG
纯化方法 affinity purified by Protein A
储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 IF=1:50-200
（石蜡切片需做抗原修复）

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

丝氨酸蛋白酶8抗体/Anti-PRSS8 产品介绍 PRSS8 is a member of the trypsin family of serine proteases. It can be found in seminal fluid and is highly expressed in prostate epithelia. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. The carboxyterminal region contains a GPI anchor sequence, which anchors prostasin to the cell surface. Phospholipase activity is thought to liberate prostasin from the cell, and cleavage of the linker region also releases prostasin. PRSS8 has been proposed as a marker for ovarian cancer, where it is up-regulated, a marker for androgen-refractory prostate cancer, where it is down-regulated, and as an inhibitor of invasiveness in breast cancer.